Citation :

Dawn VJ, Irene V R, Anitta Shaji, Sreelakshmi N P, Sumaya S, Elsa Maria John, Megha O. O, 2025. "Assessment of Effectiveness and Outcome of Letrozole Therapy Among Infertile Women at a Secondary Care Hospital: A Retrospective Study" ESP International Journal of Advancements in Science & Technology (ESP-IJAST)  Volume 3, Issue 1: 51-67.

Abstract :

The initiative seeks to investigate the efficacy of Letrozole therapy in women undergoing infertility treatment. The goal is to characterize the types of infertility histories among women getting infertility treatment and to estimate the prevalence of Letrozole use during pregnancy. This is a retrospective observational study conducted at the Gynaecology Department of Paalana Institute of Medical Science, Palakkad, Kerala. A self developed data collection form was used to collect the data. Inclusion criteria were women above the age of 20, all women having ovulation induction therapy, and infertile women getting Letrozole medication. Women who did not continue to take Letrozole were excluded. Prior to data collection, the Institution Ethics committee gave their consent. The gathered data was examined and documented. Letrozole's efficacy was statistically examined using the Chi square approach. At end of Treatment Status out of the 49 patients, 26 became pregnant, whereas the remaining 23 did not respond to treatment, meaning they did not become pregnant. This findings shows, Letrozole is an effective method of ovulation induction, particularly for individuals with anovulatory infertility.

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Keywords :

Aromatase inhibitors, Infertility, Letrozole, Reproductive system, , Ovulation induction.